What is MOTS-c?
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA Type-c) is a “mitochondrial-derived peptide” that acts as a powerful metabolic signal. While most peptides are encoded in your cell’s nucleus, MOTS-c comes directly from your mitochondria—the power plants of your cells.
At Balanced Medical Solutions, MOTS-c is often called the “Exercise Mimetic” or the “Exercise Pill.” It effectively tricks your body into thinking it just completed a high-intensity workout, triggering a massive wave of metabolic repair, fat burning, and cellular rejuvenation without the immediate physical strain.
Common Uses of MOTS-c for Balanced Medical Solutions’ San Francisco and East Bay Area Patients:
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Weight Loss & Fat Oxidation: MOTS-c is exceptional at breaking down stubborn body fat. It signals the body to stop storing fat and start burning it for fuel by activating the AMPK pathway (the same “metabolic master switch” activated by the drug Metformin).
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Improving Insulin Sensitivity: It is a potent tool for reversing insulin resistance and metabolic syndrome. By helping your muscles absorb glucose more efficiently, it stabilizes blood sugar and reduces the risk of Type 2 Diabetes.
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Boosting Physical Endurance: For active patients, MOTS-c is a “performance enhancer.” It increases ATP (cellular energy) production, allowing you to work out harder, run further, and recover much faster from strenuous activity.
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Anti-Aging & Longevity: MOTS-c levels naturally decline as we age. Restoring these levels helps protect against “inflammaging” (chronic age-related inflammation) and supports the structural integrity of your cells.
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Muscle Preservation (Anti-Sarcopenia): It helps prevent the muscle wasting that typically comes with age or rapid weight loss. It ensures that when you lose weight, you are losing fat, not the lean muscle that keeps your metabolism high.
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Cognitive Support: By reducing neuro-inflammation and improving mitochondrial health in the brain, MOTS-c is being explored for its ability to sharpen focus and protect against cognitive decline.
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Bone Density Support: Recent studies suggest MOTS-c promotes the growth of osteoblasts (bone-forming cells), making it a valuable adjunct therapy for preventing osteoporosis.
