What is PT-141 (Bremelanotide)?

PT-141, also known as Bremelanotide (brand name Vyleesi®), is a revolutionary peptide therapy that treats sexual dysfunction by targeting the brain rather than the body’s vascular system. Unlike medications like Viagra or Cialis, which only improve blood flow, PT-141 acts directly on the central nervous system to ignite the “mental spark” of desire.

It is a synthetic peptide that activates melanocortin receptors in the hypothalamus—the brain’s command center for sexual arousal. At Balanced Medical Solutions, PT-141 is used as a highly effective “on-demand” treatment for both men and women who struggle with a lack of interest or a “mental disconnect” from intimacy.

Common Uses of PT-141 for Balanced Medical Solutions’ San Francisco and East Bay Area Patients:

  • Igniting Libido and Desire: PT-141 is FDA-approved for Hypoactive Sexual Desire Disorder (HSDD) in women. It is the go-to solution for those who find that their “physical equipment” works, but their mental drive has diminished due to stress, age, or hormonal shifts.

  • “Salvage” Therapy for Men: For men who haven’t had success with PDE5 inhibitors (Viagra/Cialis) because their issue is neurological or psychological rather than purely vascular, PT-141 offers an alternative pathway to achieving a firm, reliable erection.

  • Overcoming Arousal Barriers: It helps “turn up the volume” on sexual cues. Patients report that instead of feeling like intimacy is a “chore” or “mechanical,” they feel a genuine, spontaneous urge and heightened motivation for connection.

  • Intensifying the Orgasmic Response: By stimulating the brain’s reward and pleasure centers (dopamine pathways), PT-141 can lead to more satisfying and intense sexual experiences for both partners.

  • Non-Hormonal Support: Because it works on the nervous system, PT-141 does not alter your testosterone or estrogen levels. This makes it a viable option for patients who want (or need) to avoid hormone therapy.

  • Spontaneous and Responsive Intimacy: Effects typically begin within 45 to 60 minutes and can last for up to 12 to 24 hours, allowing for a much larger window of spontaneity compared to traditional medications.

Access our complete patient education on PT-141 below to learn more:

Bremelanotide (PT-141) Patient Education – Click Here

Español: Información sobre la Terapia con Bremelanotide (PT-141) – Pulse Aquí